Endocrine Abstracts

Introduction: Autosomal dominant polycystic kidney disease (ADPKD) is an inherited kidney disease characterized by the development and growth of cysts causing a progressive kidney enlargement and the end-stage renal disease (ESRD). The incidence of brain aneurysms in patients with ADPKD is high thus screening is recommended. The association of pituitary incidentalomas and ADPKD is rarely described in the literature. All reported pituitary adenomas in patients with ADPKD were f...

Background: The association between Graves’ disease and thymic hyperplasia is well documented in the literature. Despite that it remains largely unrecognized in routine clinical practice. The lack of familiarity of usually benign nature of thymic hyperplasia associated with Graves’ disease may result in an aggressive management course, along with associated risks.Case presentation: A previously healthy 32-year-old female was admitted to hospita...

Introduction: Brown tumour is a rare, benign, tumour-like lesion of bones.The presence of brown tumour is a rare complication of uncontrolled primary, secondary or tertiary hyperparathyroidism.Brown tumours can be solitary or multifocal and are most commonly located in ribs, clavicles, pelvic girdle, extremities and facial bones (maxilla, mandible, and hard palate).A diagnosis of brown tumour in hyperparathyroidism is established by evaluation of serum calcium, phosphorus and ...

: Polycystic ovary syndrome (PCOS) is one of the most common endocrine disorders in women of reproductive age. It’s a heterogeneous functional disorder of unclear etiology. The features of PCOS are disorders of ovulation, androgen excess, polycystic ovaries; it’s associated with presence of associated risk factors for cardiovascular disease (obesity, glucose intolerance, dyslipidemia). The diagnosis of PCOS is made using the Rotterdam 2003 criteria. 23yo female patie...

Objective: To analyse the semen quality in patients with newly diagnosed non-Hodgkin lymphoma before starting the treatment.Materials and methods: We evaluated semen quality in 29 patients with non-Hodgkin lymphoma who underwent sperm banking in our clinic over a 9-year period. Semen samples were collected by masturbation after 2–7 days of sexual abstinence. Age at banking, semen volume, sperm concentration, and total and progressive sperm motility ...

Primary hyperparathyroidism (PHPT) is nowadays usually diagnosed as an asymptomatic disease but it might be related with advanced end-organ damage. Parathyroid incidentaloma (PI) is the term describing enlarged parathyroid nodules that are unexpectedly discovered on surgery or by imaging performed for nonparathyroid disorders. The recognition of PI might uncover a clinically significant PHPT with the potential for surgical cure. We retrospectively reviewed patients’ reco...

Parathyroid localization by fine needle aspiration and parathyroid hormone (PTH) washout measurement is not a widely accepted method because of possible alterations in parathyroid histology. However, when performed with technical competence this easily available method has been praised to be an immediate confirmation of enlarged parathyroid glands found on ultrasound. We retrospectively reviewed primary hyperparathyroidism (PHPT) patients with previously performed PTH washout ...

Objective: To analyse the semen quality in patients with newly diagnosed lymphoma’s before starting the treatment.Materials and methods: We evaluated semen quality in 131 patient with lymphoma who underwent sperm banking in our clinic over a 14-year period. 102 patients had Hodgkin’s lymphoma, and 29 had non-Hodgkin’s lymphoma. Semen samples were collected by masturbation after 2–7 days of sexual abstinence. Age at banking, semen volu...

Although primary hyperparathyroidism (PHPT) can be successfully cured by parathyroidectomy (PTX) and indications for surgery are well defined, a considerable number of patients do not get operated on. By evaluating referrals for PTX in our academic hospital, we might improve our approach to the care of these patients. We retrospectively reviewed patients’ hospital records with newly diagnosed PHPT between 2014 and 2020. Biochemical and clinical parameters along with resul...

Background: According to the World Health Organization, there are approximately 650 million obese adults worldwide. In Croatia almost 2/3 (65%) of adults are overweight (42%) or obese (23%), with a growing tendency both in adults and children. The surgical procedures performed to manage obesity are referred to as metabolic or “bariatric” surgery. Candidates for a bariatric surgical procedure include obese patients with a BMI ≥ 40 kg/m2(obesity class ...